With the advent of the aging society, the development of medicines for the treatment of geriatric diseases has become a hot spot. Among them, the treatment of Alzheimer's disease or medicines that improve learning and memory are one example. The number of new drug applications in this area is increasing. According to the research status at home and abroad, there is no drug that can really treat "dementia". The drugs currently on the market or in the development process mainly change the learning and memory function of dementia, and its clinical positioning is mainly to improve the learning and memory function of patients with dementia .
In the process of non-clinical effectiveness research, behavioral experiments are mainly used to study the effects of drugs on animal learning and memory functions. The internal psychological processes of humans and animals cannot be directly observed, and only the processes that occur in the brain can be speculated based on the observable stimuli. The study of memory processes in the brain can only learn or perform a certain task from humans or animals. After a certain period of time, measure their operational performance or reaction time to measure the coding form, storage capacity, retention time and the conditions on which they depend on these processes. The basis of experimental methods of learning and memory is conditioned reflex, and various methods are derived from it. At present, a large number of behavioral methods for learning and memory research have been established, each with advantages and disadvantages. Now the commonly used animal learning and memory experiment methods are briefly described as follows.
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