Shimadzu launches LC / MS / MS drug abuse method package

In recent years, drug abuse and illegal drug use have become a social problem, leading to more and more crimes and addictive tendencies of psychotropic drugs and sleeping pills. At the same time, there has been a trend towards diversification of drug abuse. Finding and confirming illegal compounds in forensic, toxicological and clinical fields requires a fast and highly sensitive analytical method.

At present, liquid chromatography quadrupole mass spectrometry (LC / MS / MS) has been used for this type of analysis. It can also provide highly selective quantitative analysis results for low concentration compounds, reducing sample preparation time and cost. And improve work efficiency. To this end, Shimadzu, which pursues the business philosophy of "Human and Earth Health", promptly launched the LC / MS / MS Drug Abuse Method Package.

Shimadzu LC / MS / MS Drug Abuse Method Package contains analysis conditions, compound information and product ion mass spectrometry [forbidden drugs (87 species), psychotropic drugs (105 species), sleeping drugs (70 species), other components (24 species )]. The method package includes optimized Synchronized Survey Scan â„¢ parameters (product ion spectrum acquisition parameters based on MRM threshold intensity) for screening analysis. And provide simultaneous analysis methods of 100 common components including prohibited drugs, psychotherapeutic drugs, sleeping drugs, and other components. Therefore, the method package frees the user from the tedious work such as the selection of separation conditions and the optimization of the mass spectrometry parameters of each target compound, and quickly carries out LC / MS / MS analysis, thereby greatly improving the efficiency of simultaneous analysis of multiple components.

Shimadzu LC / MS / MS drug abuse method package features:

1) Provide analysis solutions

The method package contains method files, which list the conditions of mass spectrometry analysis, liquid chromatography separation conditions, retention time information of each compound, report files, etc. The user can quickly start the analysis work by simply preparing the experimental conditions. Since these analytical methods have been validated in the laboratory, the time required for analytical method development can be significantly reduced.

2) Simplify the analysis process when LC / MS / MS multi-component simultaneous analysis

When performing LC / MS / MS analysis, the mass spectrometry parameters of each compound must be optimized. Since the method package already contains the optimized mass spectrometry parameters of each compound, the time and effort required for parameter optimization can be greatly reduced. For a list of compounds, please refer to the method package compound list attached to this release notice.

3) Provide optimized synchronous inspection scan parameters for screening analysis

Through the mass spectrometry database in the method package, the similarity search of the product ion scan results can be performed.

4) Easily customize the method file

LabSolutions LCMS can easily customize method files to increase or decrease target compounds to be analyzed. Moreover, the analysis parameter list in the method package can be used to create a specific new method file for the target compound to be analyzed.

5) Provide mass spectrometry database manual

The mass spectrum database manual lists each compound's mass spectrum and compound information. This manual can be used as a simple and convenient guide to confirm the analysis data.

About Shimadzu

Shimadzu Enterprise Management (China) Co., Ltd. is a local legal person company established in China in 1999 by Shimadzu Corporation to expand the scale of its business in China.

At present, Shimadzu Enterprise Management (China) Co., Ltd. has 13 branches throughout China, and its business scale is continuously expanding. There are analysis centers in Beijing, Shanghai, Guangzhou, Shenyang, and Chengdu; a network of sales agents covering 30 provinces across the country; and more than 60 technical service stations to build a complete system that provides good services to users.

As a global production base, Shimadzu has built a product production and supply system not only for Chinese customers, but also for the world, and strives to build a product production system that meets the requirements of the Chinese market. With the goal of "for the health of mankind and the earth", Shimadzu will always strive to provide users with more advanced products and more satisfactory services.

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